Insulin-Dependent Diabetes Mellitus

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Insulin-Dependent Diabetes Mellitus

From the School of Nursing (Drs Boehm, Schlenk, and Ronis and Ms Powers) and the Michigan Diabetes Research and Training Center, School of Medicine (Ms Funnell), University of Michigan, and the Department of Veteran’s Affairs (Dr Ronis), Ann Arbor, Michigan. Correspondence to Susan Boehm, PhD, Associate Professor and Dean, Student Affairs, The University of Michigan, School of Nursing, 400 Nort...

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Insulin effect on Leptin Concentration in Children with New Onset Insulin Dependent Diabetes Mellitus

Objective: Serum Leptin concentration reflects the body fat mass. There is controversial reports about the insulin effect on serum Leptin concentration. We wanted to examine the effect of insulin therapy on serum Leptin in children with new onset type I diabetes. Materials and Methods: This was a Cross-Sectional study in Children's Medical Center on 34 children who had new onset type I diabe...

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Insulin - Dependent Diabetes Mellitus Review

*Department of Microbiology and Immunology et al., 1995) and adhesion molecules (very late antigen School of Medicine 4) (Yang et al., 1993). University of North Carolina at Chapel Hill Studies of rodent models and preliminary studies in Chapel Hill, North Carolina 27599 man have shown that the completion of b cell destruc†Department of Microbiology and Immunology tion can beconsiderably delaye...

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Non-insulin-dependent diabetes mellitus.

Non-insulin-dependent diabetes mellitus (NIDDM) occurs predominantly after the age of 50 years but is not easy to distinguish from late onset insulin-dependent diabetes. It is likely that misclassification is rare in a Caucasian population. Whilst NIDDM is widely believed to be genetically determined, recent epidemiological observations have consistently revealed statistical associations betwee...

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Preventing insulin dependent diabetes mellitus.

The ultimate goal for those who care for people with insulin dependent diabetes is prevention. This seemed a futile quest until the 1 970s when the aetiology ofthe condition began to be unravelled. Insulin dependent diabetes mellitus was shown to be an autoimmune disorder with a genetic basis, strongly associated with the class II alleles DR3 and DR4. This led to a series of studies of immunosu...

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ژورنال

عنوان ژورنال: Cell

سال: 1996

ISSN: 0092-8674

DOI: 10.1016/s0092-8674(00)81106-x